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Chemically, the peptide has a molecular weight of 401.91 g/mol

Huang R-q, Ke W-l, Qu Y-h, Zhu J-h, Pei Y-y, Jiang C

The TGA says the eye disorder non-arteritic anterior ischaemic optic neuropathy (NAION) may result in permanent visual impairment and no treatment has been shown to improve visual acuity outcomes after the condition develops

doi: 10.1186/s13568-021-01213-9 222

One study on women looking at colon cancer risk found that women with a high polygenic risk score for colon cancer had a significant reduction in risk of CRC with menopausal HRT.[ref] Another study showed that several genetic variants statistically impacted the risk of breast cancer with HRT, but it concluded that more studies are needed